Collaborations & Alliances

Lilly, AstraZeneca in Alzheimer’s R&D Alliance

To co-develop MEDI1814, an antibody selective for amyloid-beta 42 (Aβ42) in Phase I development

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By: Kristin Brooks

Managing Editor, Contract Pharma

Eli Lilly and Co. and AstraZeneca have entered a worldwide agreement to co-develop MEDI1814, an antibody selective for amyloid-beta 42 (Aβ42), which is currently in Phase I development as a potential disease-modifying treatment for Alzheimer’s disease (AD). This agreement expands the collaboration related to AZD3293, a BACE inhibitor in Phase III development. AstraZeneca will receive a $30 million upfront payment from Lilly. The build-up of plaques in the brain containing the peptide a...

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